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Molecular modelling of polyphenols biosynthetic pathways and its application in gene discovery and gene modulation in living cells for pharmacogenomics purposes Print

 

Project facts

Principal investigator: Prof. Corrado Priami
Funding agency: Caritro Foundation
Duration: 33 months
Starting date: 30-Mar-2007
Euro: 69.000
Contact person: Michele Forlin

Summary

Phenols are a complex family of secondary metabolites produced by several plants. Numerous studies provide support for the bioactivity of phenolic compounds: phenols show anti-inflammatory, anti-microbial and anti-cancer activity. They also exhibit cardioprotective effects.
The primary goal of the project is to help to complete and understand the phenolic compound biosynthesis pathway, in particular the
biosynthesis of resveratrol and its derivatives, using new instruments to model and simulate dynamic biological systems.
Understanding and learning more about how phenolic compounds are synthesized can have a great impact on their use in medical field and
on their mass production as a drug.

Partner

Dr. Riccardo Velasco – Fondazione Mach

 

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