In silico experiments are performed in COSBI LAB via the integration of COSBI LAB Model and its simulation environment. Models are automatically translated into BlenX, a lower level modeling language and run with a stochastic simulation engine (based on the Gillespie algorithm).
COSBI LAB users can choose to perform:
Scanning of parameters for sensitivity analysis
Aggregated, multiple-run simulations
COSBI LAB users can simulate models directly on their personal computer or, for computationally heavy needs, COSBI LAB is integrated with:
the Cloud* (only pay for what you use, when you use it)
High-performance Computing (HPC) cluster
*COSBI is a Venus-C Partner.
HOW TO CITE AND REFERENCES
Betawb, COSBI, The Microsoft Research - University of Trento Centre for Computational and Systems Biology, http://www.cosbi.eu/index.php/research/prototypes/betawb
L. Dematté, C. Priami, A. Romanel. The Beta Workbench: a computational tool to study the dynamics of biological systems. Briefings in Bioinformatics, 9(5): 437-449, 2008 # © Oxford Journals, 2008.
Lorenzo Dematté, Roberto Larcher, Alida Palmisano, Corrado Priami, Alessandro Romanel. Programming Biology in BlenX. In Systems Biology for Signaling Networks 1:777-820, Ed. Sangdun Choi, © Springer, 2010.