Journal Papers Snazer: the simulations and networks analyzer


Abstract

Background: Networks are widely recognized as key determinants of structure and function in systems that span the biological, physical, and social sciences. They are static pictures of the interactions among the components of complex systems. Often, much effort is required to identify networks as part of particular patterns as well as to visualize and interpret them. From a pure dynamical perspective, simulation represents a relevant way-out. Many simulator tools capitalized on the “noisy” behavior of some systems and used formal models to represent cellular activities as temporal trajectories. Statistical methods have been applied to a fairly large number of replicated trajectories in order to infer knowledge. A tool which both graphically manipulates reactive models and deals with sets of simulation time-course data by aggregation, interpretation and statistical analysis is missing and could add value to simulators. Results: We designed and implemented Snazer, the simulations and networks analyzer. Its goal is to aid the processes of visualizing and manipulating reactive models, as well as to share and interpret time-course data produced by stochastic simulators or by any other means. Availability: Snazer is freely available from the COSBI website.



Paper Details

Authors

T. Mazza,  G. Iaccarino,  C. Priami

Publication

BMC Systems Biology, 4, ,

Download

/var/papers/PP/PP-0243-2009.pdf

Language

English
.