Journal Papers The identification of a series of novel, soluble non-peptidic neuropeptide Y Y2 receptor antagonists.


Abstract

The identification and subsequent optimisation of a selective non-peptidic NPY Y2 antagonist series is described. This led to the development of amine 2, a selective, soluble NPY Y2 receptor antagonist with enhanced CNS exposure.



Paper Details

Authors

L. Caberlotto,  G. Luniss,  M. Biagetti

Publication

Bioorg Med Chem Lett., 20, , 7341-4

Download

http://www.sciencedirect.com/science/article/pii/S0960894X1001526X

Language

English
.