Pathway analysis

Our research efforts are devoted to the elucidation of the mechanisms involved in metabolic and immuno-inflammatory disorders, in neurodegeneration, cancer and infectious diseases, and in the analysis of omic and clinical data following therapies or dietary regimens. We complement our research with the development and customization of computational biology algorithms in support of systems pharmacology and nutrition.

Taking care of immune-beneficial infant gut bacteria

Hunting for foods to help infants build strong immune systems, a New Zealand National Science Challenge. These studies are traditionally conducted trialing...

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Investigating Duchenne muscular dystrophy biology through plasma proteome

Identify disease biomarkers and deregulated pathways in Duchenne muscular dystrophy from omic data We developed a two-step computational workflow to extract...

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Investigating the inflammatory signaling characterizing lysosomal storage disorders (LSDs)

Develop a text-mining and systems biology framework to investigate the inflammatory signaling characterizing lysosomal storage disorders (LSDs). First...

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A QSP approach based on a graphical model to improve mRNA vaccine platforms

Analyzing and integrating multi-source knowledge and data, with the goal of clarifying the intricate biological processes involved in the mechanism of...

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