Developing a hierarchical multi-level mathematical model of glucose homeostasis
Systems Nutrition
Understanding the impact of nutrition on human metabolism in health and disease
We integrate high-dimensional data from multiple sources to build a computational framework enabling a systems-level investigation of the effect of nutrients on metabolic pathways at molecular, cellular and tissue level. We investigate how different dietary regimens can improve health by modulating metabolic pathways and shaping our microbiome. Our models support the identification of novel mechanisms and targets for metabolic disorders, paving the way for personalized nutrition approaches.